Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical ANTIBODY ApatInIb 25mg
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A selective VEGFR2 inhibitor (IC50 = 1 nM); inhibits the proliferation of HUVECs stimulated by FBS and prevents the growth of several established human tumor xenograft models
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Lkt Laboratories Busulfan, ≥98%, 10GR
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Alkyl sulfonate; DNA alkylator. CAS: 55-98-1. Additional sizes available upon request. Ships from Saint Paul, MN.
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![Medchemexpress LLC 2-(3-methoxypyridin-2-yl)-5-(trifluoromethoxy)-1H-benzo[d]imidazole | 1881276-00-1 | 98.9% | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230640.png-250.jpg)
Medchemexpress LLC 2-(3-methoxypyridin-2-yl)-5-(trifluoromethoxy)-1H-benzo[d]imidazole | 1881276-00-1 | 98.9% | 50MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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2-(3-methoxypyridin-2-yl)-5-(trifluoromethoxy)-1H-benzo[d]imidazole | 1881276-00-1 | 98.9% | 50MG
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Lkt Laboratories Propafenone Hydrochloride, ≥98%, 1GR
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β-adrenergic antagonist, Kv1.4 and K2P2 K+ channel blocker. CAS: 34183-22-7. Additional sizes available upon request. Ships from Saint Paul, MN.
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Cayman Chemical ANTIBODY IDO-IN-1 1mg
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A potent IDO inhibitor (IC50s= 59 and 12 nM for human recombinant and HeLa cell IDO, respectively); inactive against TOD (IC50 > 10 µM).
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![Medchemexpress LLC 2-Naphthalenol, 1-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]- | 152367-54-9 | 99.6% | 318.37 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-Naphthalenol, 1-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]- | 152367-54-9 | 99.6% | 318.37 | 25 MG
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EGR-1-IN-2 (compound 2) is an EGR-1 inhibitor with anti-inflammatory activity. It inhibits the formation of EGR-1-DNA complexes induced by TNF-α in HaCaT cells. This product is for research use only.
- Inhibits EGR-1-DNA complexes
- Anti-inflammatory activity
- For research use only
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Medchemexpress LLC 1,9-Diazaspiro[5.5]undecan-2-one, 1-(3,4-difluorophenyl)-9-[6-(2,2,2-trifluoroethoxy)-4-pyrimidinyl | 2761767-18-2 | 98.8% | 456.41 | 25 MG
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GJG057 is a selective, orally active inhibitor for leukotriene C4 synthase (LTC4S) with an IC50 of 44 nM. This compound exhibits anti-inflammatory activity in mouse skin inflammation and asthma models.
- Selective, orally active inhibitor for leukotriene C4 synthase (LTC4S) with an IC50 of 44 nM.
- Exhibits anti-inflammatory activity in mouse skin inflammation model and mouse asthma model.
- For research use only.
- Appearance: Solid, Off-white to light brown.
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Medchemexpress LLC KS370G 10mg | 105955-01-9 | 10 MG
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KS370G (CAS 105955-01-9) is a small-molecule research compound reported to have oral hypoglycemic and cardiovascular protective activity. It acts on pathways including TGF-beta/Smad and is supplied as a solid for preclinical pharmacology and cellular studies.
- Orally active hypoglycemic and cardiovascular protective agent.
- High reported purity: 99.71%.
- Molecular weight 283.32, formula C17H17NO3.
- Supplied as a solid suitable for preclinical and in vitro assays.
- Available in a 10 mg research sample size.
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Cayman Chemical ANTIBODY DR2313 10mg
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A PARP inhibitor (IC50 = 0.2 and 0.24 µM for PARP1 and PARP2, respectively, in nuclear rat brain extracts); selective for PARP over GAPDH, ADH, or LDH; has no effect on lipid peroxidation; prevents cell death in vitro and in vivo
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Cayman Chemical ANTIBODY INK1117 25mg
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An inhibitor of PI3Kα that is selective for p110α in vitro (IC50 = 15 nM for p110α vs. >1 µM for other isoforms, as well as for mTOR) and in cells when used at 1 µM
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Cayman Chemical ANTIBODY RGB-286638 250mg
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A multi-kinase inhibitor; inhibits a variety of kinases, including CDK2-7 and CDK9, FMS, JAK2, c-Src, GSK3β, TAK1, JNK1A1, JNK1A2, AMPK, and MEK1 (IC50s = 1-55 nM); inhibits proliferation of multiple myeloma cancer cell lines endogenously expressing mutant and wild-type p53 (EC50s = 20-70 nM), as well as patient-derived multiple myeloma cells at 50 and 100 nM; induces G1/S and G2/M cell cycle arrest and apoptosis of MM.1S human multiple myeloma cells at 50 nM; decreases tumor growth in an MM.1S mouse xenograft model at 30 and 40 mg/kg per day for 14 days
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Medchemexpress LLC HY-122218 10mg Medchemexpress, JHU-083 CAS:1998725-11-3 Purity:>98%
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Medchemexpress, HY-122218 10mg JHU-083 CAS:1998725-11-3 JHU-083, a prodrug of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Anti-CD47-InVivo-A2140-5MG-20
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Anti-mouse/human/rat CD47-InVivo reacts with mouse CD47 otherwise known as integrin-associated protein CD47 is an approximately 50 kDa glycosylated five transmembrane protein that is ubiquitously expressed by both hematopoietic cells such as T and B lymphocytes monocytes platelets and erythrocytes and non-hematopoietic cells
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Cayman Chemical ANTIBODY ARS1620 1mg
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A covalent inhibitor of K-RASG12C (IC50 = G12C (IC50s = 150 nM) over various cells expressing wild-type K-RAS (IC50s = >10 μM); induces tumor regression in a MIA-PaCa2 mouse xenograft model at 200 mg/kg; decreases tumor volume in K-RASG12C-expressing PDX mouse models
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Cayman Chemical ANTIBODY SR-12813 50mg
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A hypocholesterolemic compound that promotes the degradation of HMG-CoA reductase in various animal models; human and rabbit pregnane X receptor agonist (Kd = 41 nM; EC50 = 137 nM for hPXR in vitro) that can induce CYP3A expression in human and rabbit hepatocytes
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